RALI-OLST Weekly Talks

Automated Extraction of Protein Mutation Impacts from the Biomedical Literature

Nona Naderi (n_nad <at> encs (point) concordia (point) ca)


Wednesday 19 September 2012 at 11:30 AM

Salle 3195, Pavillon André-Aisenstadt

We present a comprehensive system to automatically extract and summarize mutation-related information from full-text research papers. The system extraction module is split into subtasks: organism analysis, mutation detection, protein property extraction and full impact analysis, including linking impacts with the causative mutation and the affected protein properties, such as molecular functions, kinetic constants, kinetic values, units of measurements, and physical quantities. The Gene Ontology (GO) is further integrated for the analysis of the detected molecular functions. The output of the presented system is populated to an OWL-DL ontology, which can then be queried to provide structured information. In addition, the performance of the system is evaluated on both external and internal corpora and databases. The results show the reliability of the approaches.

The Open Mutation Miner (OMM) system, including its components and resources, is published under the GNU Affero General Public License v3 (AGPL3) at http://www.semanticsoftware.info/open-mutation-miner.

Follow this link to subscribe to future RALI-OLST announcements.

See all the weekly talks for the year:

1991 1992 1993 1994 1995 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024